This is the first of the three walls (see the United Nations Mural and the Roots Run Deep Mural) painted for the opening of the Athen B. Gallery. It is by Ernest Doty and Ryan Montoya. The wall is absolutely huge and can be seen from 880. The wall was painted in June, 2015. Big writeup here: http://grid.vsco.co/journal/introducing-athen-b-gallery
The mural is located on the onramp to 880 at Oak Street in Jack London Square. The Doty portion is an alien-looking man with rainbows coming out of his head, holding a magic mushroom. The Montoya portion features a stylized Native American man with laser beams coming out of his forehead, holding peyote.