This mural features a person (woman?) curled up, holding her head. It says "Lower Bottoms" in the top right. It was painted by James Shields of Creative Shields in May, 2015. You can see pictures of the mural in action here:
There is also a more graffiti-style portion to the left.
The mural is located at 10th and Willow in Village Bottoms/Prescott.